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NNT: Number Needed to Treat, Part 2

Remember that the Number Needed to treat, or NNT, is the number of people we need to treat in order to have a positive impact on one person. In my last article (http://blog.dynamicchiropractic.com/research/2015/04/number-needed-to-treat-nnt/), I provided an example of looking at the NNT using a new intervention called “lifeisgreat.” At the end of the article...
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Number Needed to Treat: NNT

The “number needed to treat” or NNT is an important measure that looks at the impact of some kind of intervention by determining the number of patients one would need to treat in order to affect one additional person. This is something we can actually calculate, but it also has some theoretical sense as...
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JTASS Revisited

Early in my career, I was taught an approach to critical appraisal that began with an acronym, JTASS. This was a brief screen to determine whether or not the article I was looking at would be useful to me. The letters here stand for Journal, Title, Author)s), Site and Summary. In doing a JTASS,...
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Information Sources

In an evidence-based world, we need, well, evidence. And with so much available to choose from, how do we decide what to use. One way is to become familiar with some of the better sources of information. You already know we have good-quality journals in our profession, but beyond those and others in the...
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A Bit of Useful Information on Information Retrieval

I have a feeling that the way in which we all look for information has changed in radical ways over the past 25 years. As a younger faculty member at chiropractic college, I was an avid reader and collector of our scientific literature. Now, of course, I was also editing a number of journals...
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Case-Control Studies

A case-control study is an epidemiological study in which we look for the presence of risk factors as they relate to the presence of a condition of interest. In case-control studies we begin with a population of people, some of whom have the condition of interest (the cases) and some of whom do not...
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A Follow-Up on Publication Bias

In my role as Human Protections Administrator at Palmer College of Chiropractic I am the first person to review a proposed project’s institutional review board (IRB) application. When we conduct clinical trials, we need to reveal to our patients the risks and benefits of their participation. While the risks are often well understood, the...
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The EQUATOR Network

I know that it can frustrate the savviest of readers when they confront a paper that may help them address a clinical problem with a patient, but the paper is such that it is hard to read or to extract information. Where might one turn for help? One great website resource you may wish...
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A Little Information on Qualitative Research

Let me start by asking you a question: the last time you were in some pain, how would you have rated that pain on a scale of 0-10, where 0 meant there was no pain and 10 meant that the pain was the worst imaginable? Now imagine I ask that same question to another...
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Randomization in Clinical Trials

Randomized clinical trials (RCT) are the best means to show the effectiveness of a clinical intervention, The primary reason the RCT is so effective is that they are designed to eliminate as much as possible a selection bias. The groups are randomized to prevent that bias from occurring and then the groups are compared...
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